No association of CSF biomarkers with APOEe4, plaque and tangle burden in definite Alzheimer’s disease
نویسندگان
چکیده
Department of Neurology and Memory Clinic, Middelheim General Hospital (ZNA), Reference Centre for Biological Markers of Memory Disorders, Laboratory of Neurochemistry and Behavior, Laboratory of Neurogenetics, Laboratory of Neurobiology and Biobank, Institute Born-Bunge, University of Antwerp, Antwerpen, Belgium, Department of Nursing Sciences, Faculty of Medicine, University of Antwerp, Antwerpen, Belgium, Neurodegenerative Brain Diseases Group, Department of Molecular Genetics, VIB, Antwerpen, Belgium, Department of Neurology, University Hospital of Antwerp, Antwerpen, Belgium and Innogenetics NV,Gent, Belgium
منابع مشابه
No association of CSF biomarkers with APOEepsilon4, plaque and tangle burden in definite Alzheimer's disease.
The CSF biomarkers beta-amyloid peptide (Abeta(1-42)), total tau protein (T-tau) and tau phosphorylated at threonine 181 (P-tau(181P)) were determined in autopsy-confirmed Alzheimer's disease patients in order to study possible associations with the epsilon4 allele of APOE and density and spread of plaques (SP) and tangles (NFT). CSF levels of Abeta(1-42), T-tau and P-tau(181P) were determined ...
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